Protein patterning based on electrochemical activation of bioinactive surfaces with hydroquinone-caged biotin.
نویسندگان
چکیده
We report a protein attachment and patterning method based on a hydroquinone-caged biotin surface that generates bioactive biotin by mild electrochemical perturbation. The electrochemical activation proceeds under the buffered aqueous environment at neutral pH. It also allows site-selective generation of bioactive biotin for the immobilization of target protein by using prepatterned electrode arrays.
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ورودعنوان ژورنال:
- Journal of the American Chemical Society
دوره 126 47 شماره
صفحات -
تاریخ انتشار 2004